Yosuga no Sora – Folge 4

On their way home from school, Haruka and Kazuha are interrupted by a frantic Yahiro, who is concerned over the non-appearance of the always-responsible Akira as usual. They discover Akira at her home, collapsed due to exhaustion, and Kazuha proceeds to blame herself and her infatuation with Haruka for not noticing Akira's condition.